Application of granule packaging machine in pharmaceutical granule materials
Granules are made of medicinal material extracts and suitable excipients or fine powder of medicinal materials, and have a certain particle size. There are three types of soluble granules, suspension granules and effervescent granules. Granules can be regarded as an extension of traditional Chinese medicine decoction. When added with water, it is the same as the decoction, so it is convenient to store, transport, carry and take. The production process of granules is relatively simple, and the various processes before tablet production and tableting together with quantitative packaging constitute the entire production process of granules. The most widely used cold granules in granule packaging is the granule packaging machine. For fixed-dose packaging, a certain dose of granules is put into a film bag and the periphery is heat-sealed and then cut off. The quantification of granules includes gravimetric method and volumetric method. Two kinds of law. The gravimetric method is to take a certain weight as the next dose; and the volume method takes the same volume as a dose. Since there are gaps between the particles of the granules, this method requires the gap to be filled at least to a certain volume of the meter. rate (i.e. bulk density). The volume dosing method is easier to realize mechanization than the weighing dosing method. The process of bagging includes several steps of bag making, filling, sealing and cutting. For example, film rolls (polyethylene, paper, aluminum foil, cellophane or composite packaging materials of the above materials) are continuously fed from top to bottom and can be flattened and folded first. layer, and then carry out longitudinal sealing and heat sealing and horizontal heat sealing of the lower bottom mouth to fill a dose of powder.
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